Description
Ipamorelin / CJC-1295 (No DAC) Blend
Intended for laboratory research purposes only. Not for human consumption
This blend combines Ipamorelin (a selective ghrelin mimetic / growth hormone secretagogue) and CJC-1295 (No DAC) (also known as Mod GRF 1-29, a GHRH analog). The blend typically features a 1:1 ratio (e.g., 5mg/5mg or 10mg total per vial), leveraging complementary mechanisms: Ipamorelin via GHS-R1a/ghrelin receptor and CJC-1295 via GHRH receptor.
Key Chemical Details (Individual Components):
- CAS Number: Ipamorelin: 170851-70-4; CJC-1295 (No DAC): 863288-34-0
- Molecular Formula: Ipamorelin: C₃₈H₄₉N₉O₅; CJC-1295 (No DAC): C₁₅₂H₂₅₂N₄₄O₄₂
- Molecular Weight: Ipamorelin: 711.9 g/mol (commonly listed as 711.85–711.9; exact monoisotopic mass ≈711.39 Da); CJC-1295 (No DAC): 3367.9 g/mol (commonly listed as 3367.9–3368; exact monoisotopic mass ≈3365.89 Da)
- Amino Acid Sequence (one-letter code):
- Ipamorelin: Aib-H-D-2-Nal-D-F-K-NH₂ (Aib = α-aminoisobutyric acid; D-2-Nal = D-2-naphthylalanine; D-F = D-phenylalanine; amidated C-terminal)
- CJC-1295 (No DAC): YADAIFTQSYRKVL A QLSARKLLQDILS R -NH₂ (C-terminal amidated; note: some sources list slight variations like Ile at position 26 vs. Met, but standard is Ile)
- Full sequence (three-letter code):
- Ipamorelin: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
- CJC-1295 (No DAC): Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂
- N-terminal / C-terminal: Ipamorelin: Aib (N-terminal) / Amidated Lys (C-terminal); CJC-1295 (No DAC): Tyrosine (Tyr) / Amidated Arginine (Arg-NH₂)
- IUPAC/Full Chemical Name: Complex for each; Ipamorelin: (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-4-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide (or variants); CJC-1295 (No DAC): Long systematic name for the 29-residue amidated peptide (see PubChem for full strings)
- PubChem CID: Ipamorelin: 9831659; CJC-1295 (No DAC): 91976842 or 56841945 (variants)
- Appearance (typical research grade): White to off-white lyophilized powder
- Solubility: Readily soluble in water or aqueous buffers
- Storage: Typically -20°C (as lyophilized powder for stability); avoid repeated freeze-thaw cycles and protect from light/moisture
- Other Properties:
- Ipamorelin: Selective GHS with minimal impact on cortisol/prolactin; pentapeptide with D-amino acids and Aib for stability
- CJC-1295 (No DAC): Short-acting GHRH analog (no drug affinity complex); 29-residue chain with D-Ala2 substitution for DPP-IV resistance
Disclaimers:
- Strictly for qualified laboratory research professionals.
- Not FDA-approved; no therapeutic, diagnostic, or human-use applications
- Purity typically ≥98–99% (HPLC); batch-specific third-party Certificates of Analysis (COAs) available for identity, purity, and contaminants.
- Handle according to standard lab safety protocols.
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