Description
Key Chemical Details:
- CAS Number: 61489-71-2
- Molecular Formula: Variable/complex (glycoprotein mixture; often simplified in databases as C₉H₁₈O due to catalog placeholders, but actual structure is large heterodimeric glycoproteins)
- Molecular Weight: Variable; approximately 25,000–40,000 Da per hormone dimer (FSH ~30–35 kDa, LH ~28–30 kDa, depending on glycosylation); some vendor listings use 142.24 g/mol (from simplified database entry, not reflective of the full complex)
- Composition:
- Heterodimeric glycoproteins: Common α-subunit (~92 amino acids) + specific β-subunits (FSH β: ~111 amino acids; LH β: ~121 amino acids)
- Extensively glycosylated (N- and O-linked carbohydrates contribute to molecular weight, stability, and bioactivity)
- No single linear amino acid sequence (unlike small peptides); bioactivity measured in International Units (IU)
- PubChem CID: 21888462 (for Menotropins/Human Menopausal Gonadotrophin entry)
- Appearance (typical research grade): White to off-white lyophilized powder
- Storage: Typically -20°C (as lyophilized powder for stability); reconstituted: 2–8°C refrigerated or frozen aliquots
- Other Properties:
- Biological activity: 75 IU FSH + 75 IU LH per vial (1:1 ratio, standardized by bioassay)
- Amphiphilic and highly polar due to glycosylation and amino acid composition
- pH of reconstituted solution: Neutral to slightly acidic
- Sensitive to heat, light, and improper handling
Disclaimers:
- Strictly for qualified laboratory research use by professionals.
- Not FDA-approved; no therapeutic, diagnostic, or human/veterinary applications.
- Purity typically ≥98–99% (HPLC/potency assays); batch-specific third-party Certificates of Analysis (COAs) confirm identity, potency, and contaminants.
- Handle according to standard lab safety protocols.
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