Description
Intended for laboratory research purposes only. Not for human consumption
Selank is a synthetic heptapeptide analog of the naturally occurring immunomodulatory tetrapeptide tuftsin. It is a regulatory peptide developed for research into anxiolytic, nootropic, and neuroprotective effects, with modifications that enhance metabolic stability compared to native tuftsin.
Key Chemical Details:
- CAS Number: 129954-34-3
- Molecular Formula: C₃₃H₅₇N₁₁O₉
- Molecular Weight: 751.87–751.9 g/mol
- Amino Acid Sequence (one-letter code): TKPRPGP
- Full sequence (three-letter code): Thr-Lys-Pro-Arg-Pro-Gly-Pro
- N-terminal: Threonine (Thr); C-terminal: Proline (Pro)
- IUPAC/Full Chemical Name: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline
- PubChem CID: 11765600
- Appearance (typical research grade): White to off-white lyophilized powder
- Solubility: Readily soluble in water or aqueous buffers (may require gentle reconstitution protocols for research settings)
- Storage: Typically -20°C (as lyophilized powder for long-term stability); avoid repeated freeze-thaw cycles
- Other Properties:
- Synthetic analog of tuftsin with C-terminal Pro-Gly-Pro extension for improved stability
- Short half-life in circulation due to rapid enzymatic degradation
- Hydrophilic peptide that modulates GABAergic transmission and BDNF expression in research models
- Sensitive to proteases, heat, light, and improper pH
Disclaimers:
- Strictly for qualified laboratory research professionals.
- Not FDA-approved in this context; no therapeutic, diagnostic, or human-use applications.
- Purity typically ≥98–99% (HPLC); batch-specific third-party Certificates of Analysis (COAs) available for identity, purity, and contaminants.
- Handle according to standard lab safety protocols.
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